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- $Unique_ID{BRK02379}
- $Pretitle{}
- $Title{Can Bone Marrow Transplants Cure Anemia?}
- $Subject{anemic bone marrow transplant transplantation hemoglobin bmt red
- blood cells cell production white wbc intravenous catheters counts neutrophils
- forming producing special procedure procedures anemia bones transplants
- produce count neutrophil}
- $Volume{D-7,P-7}
- $Log{
- Red Blood Cells*0002103.scf
- Neutrophil and Monocyte (White) Blood Cells*0002104.scf
- Immune Cell Production Sites I*0004501.scf
- What is Anemia?*0009201.scf
- Symptoms of Anemia*0009202.scf}
-
- Copyright (c) 1992,1993 Tribune Media Services, Inc.
-
-
- Can Bone Marrow Transplants Cure Anemia?
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-
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-
- QUESTION: I was told by my doctor that I am mildly anemic. I started taking
- vitamins with iron, but after several weeks I am still anemic. I now read
- that there is a type of bone marrow transplant that can be done. Do you think
- that I should ask to have this done on me to cure my anemia? I would be very
- grateful to you for your opinion.
-
- ------------------------------------------------------------------------------
-
- ANSWER: Let me start with your anemia problem before I take this opportunity
- to discuss bone marrow transplantation. A mild anemia is not a serious
- condition, and a few weeks of multivitamin and iron supplement may not be
- sufficient time to see the problem resolved. Give yourself a chance, and if
- the hemoglobin does not rise to desired levels, let your doctor take a few
- more tests to determine the cause of your particular anemia, and prescribe
- some of the available remedies for the situation.
- While you are correct in relating bone marrow to blood production, anemia
- is not one of the conditions for which bone marrow transplantation (BMT) is
- indicated. Bone marrow contains the special cells that form red blood cells
- (the kind that carry the hemoglobin) as well as white blood cells (WBC) of
- several types, and platelets (that play a major role in blood clotting). WBCs
- belong to the immune system, and provide the first line of defense against
- infections. Because the marrow produces so many cells, it is an area in which
- there is active and rapid growth, and the metabolism of the cells is high.
- The main use of BMT is during the treatment of several types of cancer
- and leukemia. Both the chemicals used to fight the cancer and the radiation
- therapy which may form part of the treatment can damage the highly active bone
- marrow. Therefore the doses of both may sometimes be kept down to protect the
- sensitive marrow. These low doses may not always be totally effective against
- the cancer cells, whereas higher doses might do the complete job. In such
- cases BMT becomes an important tool.
- Bone marrow for transplantation can come from one of three sources. It
- may come from the patient (autologous). It is removed (or harvested) before
- treatment starts, and stored until it is needed. Marrow from a twin is called
- "syngeneic" while marrow from brothers or sisters, other members of the family
- or unrelated donors is called "allogeneic". The immunological makeup of the
- bone marrow must closely resemble that of the patient, a task that is not
- always easily accomplished. However, once the availability of a suitable
- supply is assured, the cancer treatment can be started.
- During the days of chemotherapy and radiation therapy, the cancer cells
- are destroyed (hopefully), but the sensitive marrow cells may also be killed.
- In addition, the loss of the living marrow removes the body's own protection
- from infectious disease. The patients must be placed in protective isolation
- during this time and until the transplanted marrow has sufficient time to
- produce the sufficient white cells to fight infection.
- The marrow is placed back into the body through intravenous catheters or
- tubes. Once in the bloodstream, these cells travel to the bone cavities where
- marrow normally grows, and begin producing cells. This begins about 14-30
- days following the transplantation. When the daily blood counts show that the
- amount of circulating WBCs (neutrophils) have reached sufficiently high
- levels, the patient may be discharged from the institution, for continuing
- outpatient follow-up care.
-
- ----------------
-
- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
-
-